The most prominent heads of state in the world begin gathering for a conference that could have a major impact on global politics. When MI-7 receives word that the Chinese premier has become the target of some high-powered killers, it falls on Johnny English to save the day. Armed with the latest high-tech weaponry and gadgets that would make even James Bond jealous, the once-disgraced agent uncovers evidence of a massive conspiracy involving some of the world's most powerful organisations, and vows to redeem his tarnished reputation by stopping the killers before they can strike.

Two lovers break up after they realize that their career goals are pulling them in different directions.